The risk factors of polymicrobial periprosthetic joint infection: a single-center retrospective cohort study

Abstract Background Periprosthetic joint infection is a serious complication after total arthroplasty and polymicrobial PJI which compose subtype of often indicate worse outcomes compared to monomicrobial periprosthetic infection. However, literature review suggested that there were limited number studies evaluating the risk factors PJI. Materials methods Between 2015 January 2019 December, 64 patients 158 in tertiary center included this study corresponding medical records scrutinized. The diagnosis was based on 2014 MSIS criteria. Logistic regression used identify association between various variables ROC curve their efficiency. Results prevalence 28.3% our cohorts. After adjusting for presence sinus, previous knee infection, isolation enterococci (OR, 3.025; 95%CI (1.277,7.164) p = 0.012), with atypical organisms 5.032;95%CI: (1.470,17.229) 0.01), gram-negative 2.255; (1.011,5.031) 0.047), streptococcus spp. 6; (2.094,17.194) 0.001), CNS (OfR, 2.183;95%CI (1.148,4.152) 0.017) related decreased an adjusted OR 0.479 ( 0.023). Conclusion This demonstrated patients. Moreover, sinus tract revisions identifying different bacterial species intraoperative specimens. Therefore, these cases, it necessary examine multiple specimens both tissue synovial fluid increasing detection rate obtaining resistance information.